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Liver diseases are widely underestimated but are increasing worldwide. Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) are the most prevalent ones. Typically, both result in steatosis (abnormal retention of fat) and inflammation with progression to fibrosis, cirrhosis, and eventually liver failure. In the past, it was associated with chronic excessive consumption of alcoholic beverages but there is evidence that binge drinking can also result in liver dysfunction. These reviews looked at the increased binge drinking and the…
We often hear or read ”a study has shown…”. However, what initially sounds convincing or serious, needs to be looked at more carefully, since there are many different types of studies that differ not only with regards to their design but also to their level of scientific evidence. Whether a health measure can be recommended or not, for example, cannot be decided based on the opinion of a few experts only. In the age of evidence-based medicine, it needs to…
Recent headlines have stated that moderate wine consumption may prevent cataracts. What are the practical implications/practical significance of these headlines? What is it all about? Age-related cataract is the leading cause of visual impairment worldwide. With an ageing population and a greater life expectancy, the number of individuals with cataract is likely to increase. A cataract is a clouding of the eye’s lens. It normally develops slowly and does not affect the vision at the beginning. However, over time and…
In three large US prospective studies, higher intake of alcoholic beverages (≥15g/day) during early adulthood was related to a higher risk of colorectal cancer later in life compared to non-drinkers. This risk was independent of the level of smoking in early adulthood and intake of alcoholic beverages during midlife. These results suggest that early adulthood may be a potential period where there is an increased susceptibility to colorectal cancer. Hur J, Smith-Warner SA, Rimm EB, Willett WC, Wu K, Cao…
The results of this large-scale prospective study with over 80,000 Chinese participants and a follow-up time of 10 years showed that participants who reported consuming between 1g and 150 g of alcohol/week had a lower risk for cardiovascular disease (CVD), cancer and total mortality compared to heavy drinker and non-drinkers. The authors explain that this study in an Asian population supports prior observations of a J-shaped association between the consumption of alcoholic beverages and chronic diseases (CVD and cancer) and…
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